Eukaryome impact on Intestine homeostasis and mucosal immunology
Paris, October 16-18, 2019
Wednesday, October 16, 2019
Session 1: Evolution and impact of parasite species in humans
09:00 am-10:50 am
Chair: Tomoyoshi Nozaki, University of Tokyo, Tokyo, Japan
09:00 am

Human lifestyles, protozoa and the gut microbiota

Laure Segurel
Musée de l'Homme, CNRS, France
09:30 am

Mastigamoeba balamuthi at the cross of evolutionary roads

Jean Tachezy
Charles University, Prague, Czech Republic
09:50 am

Exploring the biology and evolution of Blastocystis and its role in the microbiome

Anastasios Tsaousis
School of Biosciences, University of Kent, Canterbury, Canterbury, United Kingdom
10:10 am

Asymptomatic Intestinal Colonization with Protist Blastocystis Is Strongly Associated with Distinct Microbiome Ecological Patterns

Cecilia Ximenez
Unit of Experimental Medicine Laboratory of Immunology, Faculty of Medicine National University of Mexico, Mexico City, Mexico
10:30 am

The molecular basis of Trichomonads' capacity to jump between hosts and mucosal sites

Robert Hirt
Newcastle University, Newcastle, United Kingdom
Opening remark (Nancy Guillen)
08:45 am-08:55 am
Coffee break
10:50 am-11:15 am
Session 2: Cell differentiation and species diversity of unicellular eukaryotes
11:15 am-01:00 pm
Chair: Robert Hirt, Newcastle University, Newcastle, United Kingdom
11:15 am

Characterizing encystation-specific transcription factor ERM-BP in Entamoeba and identifying compounds to inhibit amebic cysts

Upinder Singh
Stanford University, United States
11:45 am

Resolving Amoebozoan encystation from Dictyostelium evo-devo, comparative genomics and transcriptomics

Pauline Schaap
University of Dundee, Dundee, United Kingdom
12:05 pm

The current molecular epidemiological scenario of Cryptosporidium, Giardia and Blastocystis in Spain. Implication for Public Health

David Carmena
Spanish National Centre for Microbiology, Madrid, Spain
12:25 pm

Cryptosporidium infection in Bangladeshi children

Carol Gilchrist
University of Virginia School of Medicine, Charlottesville, United States
12:45 pm

The periodontal microbiome: from health to disease

Julien Santi-Rocca
Science and Healthcare for Oral Welfare, Toulouse, France
Lunch buffet - "Espace Congrès"
01:15 pm-03:00 pm
Session 3: Tissue homeostasis, immune-modulatory roles of the eukaryome
03:00 pm-05:00 pm
Chair: Serge Ankri, Technion Institute, Israel
03:00 pm

Role of Innate Lymphoid Cells and Th17 in Regulation of Intestinal Infection and Inflammation

William Petri Jr
University of Virginia School of Medicine, Charlottesville, United States
03:30 pm

Commensal protozoa shape mucosal immune homeostasis

Arthur Mortha
University of Toronto, Toronto, Toronto, Canada
03:50 pm

Epithelial sentinels linking luminal danger to immune responses

Philippe Jay
Institut de Génomique Fonctionnelle, INSERM, Montpellier, France
04:10 pm

Helminth therapy – nowadays and tomorrow

Kateřina Jirků Pomajbíková
Biology Centre of the Czech Academy of Sciences, Czech Republic
04:30 pm

Contribution of fungi to gut microbiome ecology, early-life immune development and airway inflammation

Marie-Claire Arrieta
University of Calgary, Calgary, Canada
04:45 pm

Innate trained immunity in Giardia and Entamoeba infection

Stacey Burgess
UVA, Charlottesville, United States
Poster Session and Welcome Cocktail
05:15 pm-07:00 pm
Thursday, October 17, 2019
Session 4: Tissue protection and immune response to infections
09:00 am-10:50 am
Chair: Elisabeth Labruyère, Institut Pasteur, France
09:00 am

Gut mucus- protection and interaction

Malin Johansson
University of Gothenburg, Gothenburg, Sweden
09:30 am

Combined low dietary fiber and mucus-degrading gut bacteria cause lethal colitis in genetically susceptible mice

Eric Martens
Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, United States
09:50 am

Roles of the mucus layer and microbiota in innate host defense against Entamoeba histolytica

Kris Chadee
Microbiology, Immunology and Infectious Diseases, University of Calgary, Canada
10:10 am

Contribution of host immunity to the development of Entamoeba histolytica-induced liver abscess

Hannelore Lotter
Bernhard Nocht Institut for Tropical Medicine, Hamburg, Germany
10:30 am

Oxidative stress and heat stress in experimental amoebic liver abscess

Alfonso Olivos-García
Universidad Nacional Autónoma de México, Mexico City, México, Mexico
Coffee break
10:50 am-11:15 am
Session 5: Host response and cell damage upon parasite interaction
11:15 am-01:10 pm
Chair: Julio Cesar Carrero, Universidad Autonoma de Mexico, Mexico
11:15 am

Phagocytosis of Entamoeba histolytica

Alok Bhattacharya
Jawaharlal Nehru University, New Delhi, India
11:45 am

Parasite-bacteria responses to host immune stresses

Serge Ankri
Technion Institute, Haifa, Israel
12:10 pm

What determines trogocytosis and phagocytosis?

Kumiko Nakada-Tsukui
National Institute of Infectious Diseases, Tokyo, Japan
12:30 pm

Acquisition of host cell membrane proteins during Entamoeba histolytica trogocytosis

Katherine Ralston
University of California, Davis, United States
12:50 pm

Role of EhC2B, a C2 domain containing actin modulator in amoebic erythrophagocytosis

Sunando Datta
Indian Institute of Science Education and Research, Bhopal, India
Lunch buffet - "Espace Congrès"
01:15 pm-03:00 pm
Session 6: Host modulation on infection outcome
03:00 pm-05:05 pm
Chair: Iris Bruchhaus, Bernhard Nocht Institut for Tropical Medicine, Germany
03:00 pm

Host modulation by Entamoeba histolyticavia secreted  lysine and glutamic acid rich protein 2

Tomoyoshi Nozaki
University of Tokyo, Tokyo, Japan
03:30 pm

Role of Extracellular Traps promoted by intestinal parasites. Relationship with virulence

Julio Cesar Carrero
Universidad Autonoma de Mexico, Mexico City, Mexico
03:50 pm

A newly defined cullin-RING ubiquitin ligase promotes thermotolerance as part of the Intracellular Pathogen Response in C. elegans

Johan Panek
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle Upon Tyne, United Kingdom
04:05 pm

Impact of tissue components on Entamoeba histolytica migration

Elisabeth Labruyère
BCI, BAI, Institut Pasteur, Paris, France
04:25 pm

Host factors involved in Cryptosporidium invasion

Chelsea Marie
University of Virginia Health System, Charlottesville, United States
04:45 pm

The Giardia secretome and its role during Giardia-host cell interactions

Staffan G. Svärd
Uppsala University, Uppsala, Sweden
Poster Session and Finger Bites
05:20 pm-06:00 pm
Visit of Musée d'Orsay and Conference Dinner
06:30 pm-11:00 pm
Friday, October 18, 2019
Session 7: Intestinal models to study eukaryome-microbiome-host interplay
09:15 am-11:05 am
Chair: Laurence Marchat, Instituto Politécnico Nacional, ENMH, Mexico City, Mexico
09:15 am

Large Intestine On Chip for Mucus and Microbiome Studies

Nancy Allbritton
University of North Carolina, United States
09:45 am

An intestinal 3D model gives insight on amoebiasis

Arturo Aguilar
Instituto Mexicano del Seguro Social, Mexico City, Mexico
10:05 am

Synergistic Engineering of Human Intestine: Organoids Meet Organs-on-Chips

Magdalena Kasendra
Emulate Inc., Boston, United States
10:25 am

Mechanical forces and 3D topology of the colonic epithelium are critical for enteric pathogens invasion using a biomimetic human gut on a chip

Nathalie Sauvonnet
Institut Pasteur, Paris, France
10:45 am

Cells, images and numbers

Jean-Christophe Olivo Marin
Institut Pasteur, France
Coffee break
11:05 am-11:20 am
Session 8: Traffic and secretion of pathogenic factors
11:20 am-01:05 pm
Chair: Kris Chadee, University of Calgary, Canada
11:20 am

Evolution, traffic and membrane transport

Mark Field
University of Dundee, Dundee, United Kingdom
11:50 am

Vesicular trafficking in Entamoeba histolytica: From trophozoites adherence to target cells, to putative effects in the intestinal microbioma and eukaryoma

Esther Orozco
Ave IPN #2508, Centro de Investigación y de Estudios Avanzados del IPN, Mexico City, Mexico
12:10 pm

PtdIns(3,4,5)P3 binding protein screening reveals unique molecules involved in endocytic processes3 binding protein screening reveals unique molecules involved in endocytic processes

Som Lata
Jamia Millia Islamia University, New Delhi, India
12:30 pm

The ins and outs of Giardia lamblia endomembrane trafficking 

Carmen Faso
Institute of Cell Biology, University of Bern, Bern, Switzerland
12:50 pm

Histomonas meleagridis from genome to proteome

Ivana Bilic
Clinic for Poultry and Fish Medicine, University of Veterinary Meducine, Vienna, Austria
01:15 pm-03:00 pm
Session 9: Gene expression, regulation sustaining pathogenicity
03:00 pm-05:20 pm
Chair: Upinder Singh, Stanford University, United States
03:00 pm

Gene silencing and overexpression to study pathogenicity factors of Entamoeba histolytica

Iris Bruchhaus
Bernhard Nocht Institut for Tropical Medicine, Hambourg, Germany
03:30 pm

The transcriptome from a compact genome

Nancy Guillen
Institut Pasteur, France
03:50 pm

Polyadenylation machineries in intestinal parasites: latest advances in Entamoeba histolytica

Laurence Marchat
Instituto Politécnico Nacional, ENMH, Mexico City, Mexico
04:10 pm

Molecular characterization of Entamoeba histolytica tRNA genes

Samie Amidou
Department of Microbiology, University of Venda, Venda, South Africa
04:30 pm

Entamoeba glycan biosynthesis genes, how the lipopeptidophosphoglycan (LPPG) might be made

Michael Duchene
Institute of Specific Prophylaxis and Tropical Medicine, Vienna, Austria
04:50 pm

Probiotics as anti-Giardia defenders: determination of the control mechanism

Jana Alazzaz
National museum of natural history, Paris, France
05:05 pm

Identification of drugs with activity against multiple pathogenic amoebae

Gretchen Ehrenkaufer
Infectious Disease, lab of Dr. Upinder Singh, Stanford School of Medicine, Stanford, Ca, United States
05:30 pm-06:00 pm


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